![]() Symptoms of an overdose include:Īn overdose can result in death due to convulsions. In some people, sudden withdrawal may cause tremors.Īlthough it’s extremely rare, it’s also possible to overdose on caffeine. Other symptoms of caffeine withdrawal include: The blood vessels in your brain become used to caffeine’s effects so if you suddenly stop consuming caffeine, it can cause a headache. This is primarily linked to caffeine withdrawal. ![]() Some people consider coffee to be a health drink, but like most foods, over indulging can cause side effects.įor example, too much caffeine can give you headaches. These benefits are limited to people who drink high-octane coffee, not decaf. Studies have also found that people who drink coffee regularly have a lower risk of developing Alzheimer’s and dementia, and cut suicide risk by 45 percent. You’ll feel more awake and less tired, so it’s a common ingredient in medications to treat or manage drowsiness, headaches, and migraines. ![]() When it reaches your brain, the most noticeable effect is alertness. If you want to decrease the amount of caffeine you take, it’s best to decrease your consumption slowly.Ĭaffeine acts as a central nervous system stimulant. Other factors like your age, body mass, and overall health can determine your tolerance to caffeine, too. If you’re using a mug or getting your fix at a coffee house, chances are you’re drinking 16 ounces or more, so reading labels is important.Īs you consume the same amount of caffeine on a daily basis, your body develops a tolerance to it. Keep in mind that a standard size cup of coffee is eight ounces. According to the Mayo Clinic, it’s safe for most healthy adults to consume up to 400 milligrams of caffeine per day. At a minimum, you may feel more energetic, but over time, too much caffeine may cause withdrawal symptoms. This ingredient almost always causes some symptoms. Even some medications may contain caffeine without your knowledge. It’s tasteless, so you won’t necessarily know if it’s in your food either. Imminent cardiac arrest in caffeine toxicity should prompt intra-lipid therapy to scavenge the free serum caffeine.Caffeine provides no nutritional value on its own. Caffeine exhibits ideal characteristics to be dialyzed, including low protein binding (36%), low molecular size (194), and a small volume of distribution (0.6 to 0.8 L/kg). Hemodialysis has been effective in severe, life-threatening caffeine ingestions. Īctivated charcoal can bind caffeine if the ingestion is recent, and repeated doses can help diminish serum levels via the enterohepatic circulation. Vasopressors, such as vasopressin or phenylephrine, can be used to maintain blood pressure (goal mean arterial pressure greater than 65 mm Hg) without worsening tachycardia. Procainamide, lidocaine, or bicarbonate have also been utilized for the treatment of tachydysrhythmias. Beta-blockade with esmolol is useful for tachycardia. Hydration may be oral in minor cases, yet severe cases benefit from intravenous (IV) hydration. The primary treatment for minor caffeine ingestion is supportive. įatal caffeine overdose is relatively uncommon, and treatment data is limited to case reports. ![]() Cardiac monitoring allows evaluation of heart rate and early recognition of dysrhythmias such as ventricular ectopy or fibrillation. An electrocardiogram may demonstrate tachycardia, ST-segment depressions, or T-wave inversions. It is also important to obtain serum myoglobin and creatine kinase levels to monitor for rhabdomyolysis. Caffeine toxicity can result in hypokalemia, hypocalcemia, hyponatremia, and hyperglycemia. Ī venous blood gas may demonstrate anion gap metabolic acidosis, which can be severe. Lethal blood levels are typically above 80 to 100 mg/L, although one case occurred at 15 mg/L. Although not available in all hospitals, serum caffeine levels are generally obtained with an immunoassay. Serum caffeine levels can guide prognosis and therapy. Routine serum laboratory evaluations can be useful in drug overdose cases, especially in the setting of unstable vital signs, seizures, or altered sensorium.
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